How Does Viagra Work?
Viagra is the chemical compound Sildenafil Citrate, and is used to treate erectile dysfunction.
The mechanism of Viagra involves the release of nitric oxide in the penis. This results in increased levels of cyclic guanosine monophosphate,
leading to smooth muscle relaxation of the intimal cushions of the helicine arteries,
resulting in increased inflow of blood and an erection. Viagra increases the hardness and duration of the erection.
The molecular structure of Viagra is similar to that of cGMP and acts as a competitive binding agent of PDE5 in the corpus cavernosum, resulting in more cGMP and better erections. Viagra activates and causes an erection only when the taker is sexual aroused.
Sildenafil is metabolised by liver enzymes and processed by both the liver and kidneys. If taken with a high-fat meal, absorption is reduced. Viagra should be taken with a light meal, or about 30 minutes before sexual activity.
